Scientific papers
Scientific papers
Explore scientific papers involving Wisepill Smart Pillboxes and real-time medication adherence monitoring.
Scientific papers and implementation research
Wisepill technologies have supported medication adherence research, clinical trials and treatment programmes across a wide range of settings and conditions.
Measurement evidence
These papers evaluate Wisepill as an adherence measure through comparison, agreement, validity, reliability or prediction of a clinical outcome. Studies that only use Wisepill to measure an intervention are not marked.
83 scientific papers shown
A Stepped Care, Peer-Delivered Intervention to Improve Substance Use and HIV Medication Adherence in Primary Care in South Africa (Project Khanya): Protocol for a Hybrid Type 2 Effectiveness-Implementation Randomized Controlled Trial
View scientific paper →Cost-effectiveness analysis of implementing a medication monitor and differentiated care approach among people with TB in South Africa
View scientific paper →
Measurement evidence
Comparing Self-Reports, Pill Counts, and Electronic Devices in Assessing Antiretroviral Therapy Adherence and its Association With Viral Suppression in Adolescents Living With HIV
Compared Wisepill, self-report and unannounced pill count and their associations with viral suppression.
View scientific paper →Acceptability of Suubi+Adherence intervention to improve ART adherence in Southern Uganda: A qualitative analysis
View scientific paper →
Measurement evidence
Feasibility, acceptability and validity of electronic adherence monitoring among adolescents in Zimbabwe: a mixed methods study
Evaluated Wisepill RT2000 validity against pill count while also assessing technical feasibility and acceptability.
View scientific paper →Addressing health literacy gaps in adjuvant endocrine therapy adherence: Post hoc insights from a randomized remote monitoring trial
View scientific paper →Absorbing Markov chain model of PrEP drug adherence to estimate adherence decay rate and probability distribution in clinical trials
View scientific paper →Positive STEPS: Enhancing Medication Adherence and Achieving Viral Load Suppression in Youth Living With HIV in the United States—Results From an Efficacious Stepped Care, Randomized Controlled Trial
View scientific paper →Symptom Monitoring App Use Associated With Medication Adherence Among Women Survivors of Breast Cancer on Adjuvant Endocrine Therapy
View scientific paper →Treatment adherence and clinical outcomes amongst people with drug-susceptible tuberculosis using medication monitor and differentiated care approach compared with standard of care in South Africa: a cluster randomized trial
View scientific paper →A Pilot Randomized Control Trial of the Striving Towards EmPowerment and Medication Adherence (STEP-AD) Intervention for Black Women Living with HIV
View scientific paper →Remote Monitoring App for Endocrine Therapy Adherence Among Patients With Early-Stage Breast Cancer: A Randomized Clinical Trial
View scientific paper →Acceptability of a Digital Adherence Tool Among Patients With Tuberculosis and Tuberculosis Care Providers in Kilimanjaro Region, Tanzania: Mixed Methods Study
View scientific paper →Digital Adherence Technologies Linked to Mobile Money Incentives for Medication Adherence Among People Living With Tuberculosis: Mixed Methods Feasibility and Acceptability Study
View scientific paper →Acceptability and feasibility of long-term, real-time electronic adherence monitoring of HIV pre-exposure prophylaxis (PrEP) use among young women in Kenya: A mixed methods study
View scientific paper →Social networks and HIV treatment adherence among people with HIV initiating treatment in rural Uganda and peri-urban South Africa
View scientific paper →Implementation bottlenecks of real time medication monitoring (evriMED) for improving adherence to anti-TB drugs among people with tuberculosis in Kilimanjaro, Tanzania
View scientific paper →Breaking down relationship barriers to increase PrEP uptake and adherence among adolescent girls and young women in Kenya: safety and preliminary effectiveness results from a pilot cluster-randomized trial
View scientific paper →The feasibility, acceptability, and preliminary impact of real-time monitors and SMS on tuberculosis medication adherence in southwestern Uganda: Findings from a mixed methods pilot randomized controlled trial
View scientific paper →Acceptability of using the medication monitor and experience of a differentiated care approach for TB treatment adherence among people living with TB in South Africa
View scientific paper →Electronic Antiretroviral Therapy Adherence Monitors and Associated Interventions Improve Adolescent–Caregiver Relationships and Self-Efficacy Among Adolescents and Young Adults with HIV in Uganda
View scientific paper →Mental Health, Self-Care, and Engagement in Care among Black Women Living with HIV
View scientific paper →Acceptability and Feasibility of Providing Adherence Feedback Based on Tenofovir Diphosphate in Dried Blood Spots: Results from a Pilot Study Among Patients and Providers in Cape Town, South Africa
View scientific paper →Qualitative study exploring the feasibility of using medication monitors and a differentiated care approach to support adherence among people receiving TB treatment in South Africa
View scientific paper →
Measurement evidence
Predicting viral load suppression by self-reported adherence, pharmacy refill counts and real time medication monitoring among people living with HIV in Tanzania
Compared Wisepill, self-report and pharmacy refill counts for predicting viral-load suppression.
View scientific paper →
Measurement evidence
Monitoring adherence to antiretroviral therapy among adolescents in Southern Uganda: comparing Wisepill to Self‐report in predicting viral suppression in a cluster‐randomized trial
Measured agreement with self-report and compared both measures’ sensitivity, specificity and viral-suppression prediction.
View scientific paper →A Mixed-Methods Study of the Technical Feasibility and Patient Acceptability of a Real-Time Adherence Monitor in Breast Cancer Survivors Taking Adjuvant Endocrine Therapy
View scientific paper →Randomized Controlled Pilot Trial of a Low-Touch Remotely-Delivered Values Intervention to Promote Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors
View scientific paper →Using an Electronic Medication Event–Monitoring System for Antiretroviral Therapy Self-Management Among African American Women Living With HIV in Rural Florida: Cohort Study
View scientific paper →Moderating effects of social support on the relationship between substance use disorders and HIV viral load and medication adherence among Black women living with HIV in the United States
View scientific paper →Effect of Digital Adherence Tools on Adherence to Antiretroviral Treatment Among Adults Living With HIV in Kilimanjaro, Tanzania: A Randomized Controlled Trial
View scientific paper →A review of features and characteristics of smart medication adherence products
View scientific paper →Acceptability of the Medication Event Reminder Monitor for Promoting Adherence to Multidrug-Resistant Tuberculosis Therapy in Two Indian Cities: Qualitative Study of Patients and Health Care Providers
View scientific paper →Evaluation of adherence monitoring system using evriMED with a differentiated response compared to standard of care among drug-sensitive TB patients in three provinces in South Africa: a protocol for a cluster randomised control trial
View scientific paper →Project Khanya: results from a pilot randomized type 1 hybrid effectiveness-implementation trial of a peer-delivered behavioural intervention for ART adherence and substance use in HIV care in South Africa
View scientific paper →“I Wish to Continue Receiving the Reminder Short Messaging Service”: A Mixed Methods Study on the Acceptability of Digital Adherence Tools Among Adults Living with HIV on Antiretroviral Treatment in Tanzania
View scientific paper →The Impact of Disease Stage on Early Gaps in ART in the “Treatment for All” Era—A Multisite Cohort Study
View scientific paper →Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions
View scientific paper →Evaluation of the Acceptability of the Medication Event Reminder Monitor for Promoting Adherence to Multidrug-Resistant Tuberculosis Therapy in India: Qualitative Study of Patients and Healthcare Providers
View scientific paper →Acceptability and Feasibility of Digital Adherence Technology (DAT) in TB REACH project in Ukraine (wave 6)
View scientific paper →Drones and digital adherence monitoring for community-based tuberculosis control in remote Madagascar: A cost-effectiveness analysis
View scientific paper →Mobile Health Technologies May Be Acceptable Tools for Providing Social Support to Tuberculosis Patients in Rural Uganda: A Parallel Mixed-Method Study
View scientific paper →
Measurement evidence
Measuring Antiretroviral Adherence among Young People Living with HIV: Observations from a Real-Time Monitoring Device versus Self-Report
Compared Wisepill with self-reported ART adherence and examined associations with viral suppression.
View scientific paper →Digital Monitoring Technologies Could enhance Tuberculosis Medication Adherence in Uganda: Mixed Methods Study
View scientific paper →Implementation and effectiveness of evriMED with short messages service (SMS) reminders and tailored feedback compared to standard care on adherence to treatment among tuberculosis patients in Kilimanjaro, Tanzania: proposal for a cluster randomized controlled trial
View scientific paper →Implementation of Medication Event Reminder Monitors among patients diagnosed with drug susceptible tuberculosis in rural Viet Nam: A qualitative study
View scientific paper →Perceptions of drones, digital adherence monitoring technologies and educational videos for tuberculosis control in remote Madagascar: a mixed method study protocol
View scientific paper →
Measurement evidence
Short- and Long-Term Pharmacologic Measures of HIV Pre-exposure Prophylaxis Use Among High-Risk Men Who Have Sex With Men in HPTN 067/ADAPT
Compared Wisepill dosing records with short- and long-term pharmacologic measures of PrEP use.
View scientific paper →Correlation of hair and plasma efavirenz concentrations in HIV-positive South Africans
View scientific paper →A triaged real-time alert intervention to improve antiretroviral therapy adherence among young African American men who have sex with men living with HIV: Focus group findings
View scientific paper →Digital adherence technologies for the management of tuberculosis therapy: mapping the landscape and research priorities
View scientific paper →Brief Report: Appraising Viral Load Thresholds and Adherence Support Recommendations in the World Health Organization Guidelines for Detection and Management of Virologic Failure
View scientific paper →Positive STEPS - a randomized controlled efficacy trial of an adaptive intervention for strengthening adherence to antiretroviral HIV treatment among youth: study protocol
View scientific paper →
Measurement evidence
Pilot evaluation of a second-generation electronic pill box for adherence to Bedaquiline and antiretroviral therapy in drug-resistant TB/HIV co-infected patients in KwaZulu-Natal, South Africa
Compared Wisepill readings with self-report and pill count, including their ability to identify non-adherence.
View scientific paper →Why it Worked: Participants’ Insights into an mHealth Antiretroviral Therapy Adherence Intervention in China
View scientific paper →Adherence Measurements in HIV: New Advancements in Pharmacologic Methods and Real-Time Monitoring
View scientific paper →Interventions to improve antiretroviral therapy adherence among adolescents in low- and middle-income countries: A systematic review of the literature
View scientific paper →Feasibility and Acceptability of a Task-Shifted Intervention to Enhance Adherence to HIV Medication and Improve Depression in People Living with HIV in Zimbabwe, a Low Income Country in Sub-Saharan Africa
View scientific paper →
Measurement evidence
Comparison of Measures of Adherence to Human Immunodeficiency Virus Preexposure Prophylaxis Among Adolescent and Young Men Who Have Sex With Men in the United States
Compared Wisepill estimates with self-report and tenofovir levels in hair and dried blood spots.
View scientific paper →Cognitive behavioral therapy for body image and self-care (CBT-BISC) in sexual minority men living with HIV: A randomized controlled trial
View scientific paper →Usability of a Medication Event Reminder Monitor System (MERM) by Providers and Patients to Improve Adherence in the Management of Tuberculosis
View scientific paper →Optimizing Pre-Exposure Antiretroviral Prophylaxis Adherence in Men Who Have Sex with Men: Results of a Pilot Randomized Controlled Trial of "Life-Steps for PrEP"
View scientific paper →
Measurement evidence
Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes?
Compared Wisepill with five other adherence measures for predicting virologic failure and drug resistance.
View scientific paper →Promoting Engagement in the Drug Resistant TB-HIV Care Continuum in South Africa PRAXIS Study (PRospective study of Adherence in M/XDR-TB Implementation Science)
View scientific paper →The Daily Relationship Between Aspects of Food Insecurity and Medication Adherence Among People Living with HIV with Recent Experiences of Hunger
View scientific paper →Can Short-Term Use of Electronic Patient Adherence Monitoring Devices Improve Adherence in Patients Failing Second-Line Antiretroviral Therapy? Evidence from a Pilot Study in Johannesburg, South Africa
View scientific paper →Feasibility, Acceptability, and Tolerability of Targeted Naltrexone for Nondependent Methamphetamine-Using and Binge-Drinking Men Who Have Sex with Men
View scientific paper →Feasibility of Real Time Medication Monitoring Among HIV Infected and TB Patients in a Resource-Limited Setting
View scientific paper →SMS reminders plus real-time adherence monitoring improve adherence to antiretroviral therapy in rural Uganda
View scientific paper →A pilot study of a nurse-delivered cognitive behavioural therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
View scientific paper →Tenofovir-based oral preexposure prophylaxis prevents HIV infection among women
View scientific paper →
Measurement evidence
Duration of antiretroviral therapy adherence interruption is associated with risk of virologic rebound as determined by real-time adherence monitoring in rural Uganda
Tested whether Wisepill-detected treatment interruptions predicted HIV virologic rebound.
View scientific paper →Cell Phone-Based and Adherence Device Technologies for HIV Care and Treatment in Resource-Limited Settings: Recent Advances
View scientific paper →A Randomized Controlled Trial of Real-Time Electronic Adherence Monitoring With Text Message Dosing Reminders in People Starting First-Line Antiretroviral Therapy
View scientific paper →Improving Adherence to Antiretroviral Therapy with Triggered Real Time Text Message Reminders: the China through Technology
View scientific paper →
Measurement evidence
Real-time Adherence Monitoring of Antiretroviral Therapy Among HIV-infected Adults and Children in Rural Uganda
Assessed validity against viral suppression and compared Wisepill with weekly IVR/SMS self-report.
View scientific paper →Real-time Medication Adherence Monitoring Intervention: Test of Concept in People Living With HIV Infection
View scientific paper →Monitoring Microbicide Gel Use with Real-Time Notification of the Container’s Opening Events: Results of the CAPRISA Wisebag Study
View scientific paper →Feasibility and Acceptability of a Real-Time Adherence Device among HIV-Positive IDU Patients in China
View scientific paper →Optimizing network connectivity for mobile health technologies in sub-Saharan Africa
View scientific paper →Improving medication adherence in diabetes type 2 patients through Real Time Medication Monitoring: a Randomised Controlled Trial to evaluate the effect of monitoring patients’ medication use combined with short message service (SMS) reminders
View scientific paper →
Measurement evidence
Real-Time Adherence Monitoring for HIV Antiretroviral Therapy
Compared Wisepill adherence with unannounced pill counts, self-report, earlier MEMS monitoring and HIV RNA.
View scientific paper →No scientific papers match your search
Try a different title word or select all years.